DISCUSS THE FACTORS THAT INFLUENCE RADIATION RESPONSE IN CANCERS AND NORMAL TISSUES.Discuss the factors that influence radiation response in cancers and normal tissues

DISCUSS THE FACTORS THAT INFLUENCE RADIATION RESPONSE IN CANCERS AND NORMAL TISSUES.Discuss the factors that influence radiation response in cancers andnormal tissues
a) Define and explain the phenomena ofi) “potentially lethal damage repair” andii) “sublethal damage repair” in cells after irradiation.(4marks)b) List the mechanisms by which a drug can sensitize tumour cells toradiation.(3marks)c) Define the terms “volume doubling time” and “potential volumedoubling time” in tumours. Explain the factors that influence thedifference in volume doubling time and potential volume doubling timein tumours.(3marks)Question 6a) Discuss the factors that influence radiation response in cancers andnormal tissues.(7marks)b) Discuss the role of normal tissue vasculature in the radiation response. (3marks)

 
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